How CHANTIX (varenicline) Works

To understand how CHANTIX is believed to work, it’s important to know how the nicotine from cigarettes affects you.

When you smoke, nicotine is sent to your brain, where it attaches to nicotine receptors. A chemical called dopamine is released, making you feel good. Then your dopamine levels drop. This makes you want another cigarette.

CHANTIX attaches to nicotine receptors in the brain, so that nicotine can’t. With CHANTIX, dopamine is still released, but less so than with nicotine. It is believed that these actions are how CHANTIX may help you quit smoking.

Please see below for CHANTIX Important Safety Information and links to full Prescribing Information and Medication Guide.